The obvious point is that many of the most successful people in any field had what could have been a career-ending setbacks. The difference...failure led to inner motivation which eventually led to success! With a positive attitude, a program, patience, and persistence, you can get amazing results.
In work, the greatest satisfaction lies in the satisfaction of stretching yourself, using your abilities and making them expand, and knowing that you have accomplished something that could have been done only by your unique apparatus. This is really the center of life, and those who never orient themselves in this direction are missing more than they ever know. Kenneth Alsop.